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Secrets of the Skin

Effects of coenzyme Q10 on the skin: Mechanism of action, sources and application in cosmetology

The skin, being the outermost human organ, is directly exposed to harmful environmental factors that lead to damage that requires intensive regeneration. These processes require a large amount of energy and a properly regulated cellular metabolism. With age, both energy production and mitochondrial activity decline, leading to cellular dysfunction and visible structural changes such as wrinkles and loss of elasticity. The main culprits of this damage are reactive oxygen species (ROS), which are produced both by changes in cellular respiration and by exposure to UV radiation. These agents not only damage lipid membranes and DNA, but also structural and catalytic proteins, impairing the energy metabolism of the skin.

Coenzyme Q10, also known as ubiquinol, is a powerful fat-soluble antioxidant that is synthesized naturally in the body.

It plays important roles as a component of the electron transport chain in mitochondria, where it acts as an electron transporter, and as an antioxidant both intracellularly and extracellularly. It plays a key role in cellular respiration, enabling the production of adenosine triphosphate (ATP), which is the primary source of energy for many cellular processes, including the synthesis of collagen and elastin, structural proteins, key to skin elasticity and firmness. Its antioxidant properties protect skin cells from free radical damage, helping to reduce the appearance of wrinkles and improve overall skin texture.

Sources of coenzyme Q10

Coenzyme Q10 is produced endogenously in the human body, but can also be supplied with food. It is synthesized in the cytosol from fatty acids and tyrosine, with the participation of vitamins such as B2, B6, B12, pantothenic acid and folate. Its natural levels can decrease with age, as well as as as a result of restrictive diets that do not contain sufficient amounts of the aforementioned ingredients. Rich sources of Q10 in the diet are meat, liver, fatty fish such as sardines and tuna, as well as broccoli, wheat germ and various oils. Note that Q10 is sensitive to heat, which can reduce its content in food during cooking.

Application in cosmetology

In cosmetology, Q10 is used primarily in anti-aging products as an antioxidant ingredient that counteracts the degradation of the skin’s structural components. Topical application of products containing Q10 can protect the skin from free radicals and help reduce the appearance of wrinkles and improve the overall condition of the skin. Coenzyme Q10 is also an ingredient in dietary supplements that promote endogenous production of Q10, especially in the elderly, whose natural ability to synthesize it may be diminished.


In summary, coenzyme Q10 is an essential ingredient that promotes the health and youthful appearance of the skin through its energy and protective effects. Q10 supplementation, whether in the form of diet, cosmetics or cosmetic treatments, can make a significant contribution to improving skin function, especially in the context of aging.